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The main organ(s) of the integumentary system is (are) the:

  1. Nails.

  2. Hair.

  3. Skin.

  4. Sweat glands.

The correct answer is: Skin.

The integumentary system is chiefly comprised of the skin, which serves as the primary organ in this system. Skin plays a vital role in protecting the body from external threats, regulating body temperature, and providing sensory information due to its rich nerve supply. It also functions as a barrier to pathogens and aids in the prevention of water loss. While nails, hair, and sweat glands are important components of the integumentary system, they are considered appendages of the skin rather than primary organs. Nails and hair provide protection and enhance sensory function, while sweat glands contribute to thermoregulation by aiding in the body's ability to cool itself through perspiration. However, the skin itself encompasses these structures and is responsible for the overarching functions attributed to the integumentary system. Therefore, recognizing the skin as the main organ highlights its essential role in maintaining the body’s overall health and function.